Understanding Li-Fraumeni Syndrome (LFS)
Li-Fraumeni Syndrome (LFS) is a rare, inherited disorder that significantly increases the risk of developing various types of cancer, often at a young age. It’s caused by mutations in the TP53 gene, a crucial tumor suppressor, making affected individuals more susceptible to cancers like breast cancer, sarcomas, brain tumors, and more.
Working on LFS has been an eye-opening experience. The complexity of the genetic mutations and their effects on cancer risk continue to challenge researchers, but it also provides a unique opportunity to explore innovative approaches to cancer risk prediction. …